Heuristic algorithms in computational molecular biology

Special Topics in Computational Molecular Biology: Post Genomic Algorithms

The recent publications of the genomic sequence of large Eukaryotic mammals [4, 7] are a landmark for Molecular Biology. The whole genome sequence is a natural starting point for many investigations, and these papers contain a tantalizing glimpse into the biology of the future. It is also remarkable, and usually overlooked, that most of the conclusions in these papers were based on a computatio...

Computational Molecular Biology

Computational Molecular Biology

Utilization of primary and secondary structure elements to predict a protein's propensity to form amyloids.

Computational Molecular Biology

Computational prediction of protein subcellular locations in eukaryotes facilitates experimental design and proteome analysis. We provide a short review on recent development of computational tools and our experience in evaluating some of these tools. Classical secretomes can be relatively accurately predicted using computational tools to predict existence of a secretory signal peptide and to r...

Parallel Algorithms for Computational Biology

Bioinformatics algorithms are computationally demanding and most of them are compute intensive. Hence we require huge amount of computing power. High Performance Computing as been traditionally believed to be an expensive affair. In this paper we investigate techniques that have been used to parallelize conventional algorithms, coding patterns and architectural enhancements of platforms for bet...